Table 1.
Baseline participant characteristics for those with concordant cotinine values at baseline and at 48 weeks (n=412).
| Total (n=412) | ‘Non-Smokers’ (n=293) | ‘Current Smokers’ (n=119) | p-value ‘Current vs. Non-smokers’ | |
|---|---|---|---|---|
|
| ||||
| Mean (±SD) or % | p-value | |||
| Demographics | ||||
| Age, years | 49.6 (12.2) | 49.4 (12.7) | 50.1 (10.8) | 0.540 |
| Female gender | 73 | 75 | 67 | 0.089 |
| Caucasian race | 80 | 80 | 79 | 0.842 |
| BMI, kg/m2 | 30.0 (7.5) | 30.2 (7.8) | 29.4 (6.9) | 0.301 |
| CV disease | 27.4 | 27.7 | 26.9 | 0.876 |
| Respiratory disease | 18.8 | 15.9 | 26.1 | 0.017 |
| RA Characteristics | ||||
| Dis. duration, mo. | 3.7 (6.6) | 3.8 (6.5) | 3.4 (6.9) | 0.566 |
| DAS-28 | 5.8 (1.1) | 5.8 (1.0) | 5.8 (1.1) | 0.440 |
| ESR, mm/hr | 32.8 (24.0) | 32.9 (23.9) | 32.6 (24.3) | 0.894 |
| Swollen joints | 12.5 (5.7) | 12.4 (5.7) | 12.8 (5.8) | 0.515 |
| Tender joints | 14.0 (6.6) | 13.7 (6.5) | 14.7 (6.9) | 0.157 |
| Patient global (0–10) | 5.9 (2.2) | 5.6 (2.2) | 6.7 (2.0) | <0.001 |
| Physician global (0–10) | 6.4 (1.7) | 6.3 (1.7) | 6.7 (1.7) | 0.030 |
| HAQ (0-3) | 1.2 (0.4) | 1.2 (0.4) | 1.3 (0.4) | 0.067 |
| Functional Status | ||||
| I | 25 | 27 | 20 | |
| II | 54 | 55 | 52 | 0.022* |
| III | 21 | 18 | 28 | |
*
Mantal-Haenszel Chi-Square.
BMI = body mass index, CV = cardiovascular, RA = rheumatoid arthritis, DAS-28 = disease activity score in 28 joints, ESR = erythrocyte sedimentation rate, HAQ = health assessment questionnaire.