Table 3.

Spearman correlations among changes in 5α-androstane-3α,17β-diol glucuronide, sex steroid hormones and sex hormone binding globulin, pre- and post-finasteride treatment, among treatment-compliant men in the Prostate Cancer Prevention Trial finasteride arm

	Δ3α-dG2	Δ T	Δ E1	Δ E2	Δ Free T	Δ Free E2
Δ T3	0.041 (0.11)
Δ E1	0.08 (<.01)	0.23 (<.0001)
Δ E2	0.03 (0.29)	0.36 (<.0001)	0.54 (<.0001)
Δ Free T	0.06 (<.04)	0.92 (<.0001)	0.22 (<.0001)	0.33 (<.0001)
Δ Free E2	0.04 (0.20)	0.26 (<.0001)	0.52 (<.0001)	0.95 (<.0001)	0.32 (<.0001)
Δ SHBG6	−0.03 (0.22)	0.37 (<.0001)	0.06 (<.03)	0.17 (<.0001)	0.05 (0.05)	−0.09 (<.001)

¹Spearman Correlation (p value), pairwise deletion of missing values, N=1,226 – 1,247

²5α-androstane-3α,17β-diol glucuronide

³Testosterone

⁴Estrone

⁵Estradiol

⁶Sex Hormone Binding Globulin