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. Author manuscript; available in PMC: 2013 Nov 1.
Published in final edited form as: Am J Surg. 2012 Jun 29;204(5):741–750. doi: 10.1016/j.amjsurg.2012.02.016

Figure 1.

Figure 1

Schematic structure of adenoviral vectors. Several important structural features are reflected including wild type or Cox2-controlled replication, capsid fiber modification by RGD or 5/3, and insertion of ADP and transgene luciferase or human interferon α into the adenoviral E3 region: 1. RGD-CMV-IFN (replication-deficient control); 2. 5/3-CMV-IFN (replication-deficient control); 3.RGDCox2CRAd-F; 4. 5/3Cox2CRAd-F; 5. 5/3WtΔE3ADP-Luc; 6. 5/3WtΔE3ADP-IFN; 7. 5/3Cox2CRAdΔE3ADP-Luc; 8. 5/3Cox2CRAdΔE3ADP-IFN.