Table 3.

Results for all NHL and NHL subtypes for 6p21.3 region, pooled results, Mayo Clinic case-control study of NHL, 2002-2008.

					All NHL		CLL/SLL		Follicular Lymphoma		DLBCL
rsID	Gene	Position	Minor Allele	MAF	OR* (95% CI)	p-trend	OR* (95% CI)	p-trend	OR* (95% CI)	p-trend	OR* (95% CI)	p-trend
rs3093986	LOC†	31601400	A	0.21	0.80 (0.69, 0.93)	0.0045	0.84 (0.67, 1.04)	0.11	0.57 (0.43, 0.75)	8.5E-05	0.80 (0.60, 1.07)	0.13
rs2857597‡	AIF1	31692979	A	0.28	0.77 (0.67, 0.88)	0.00019	0.85 (0.69, 1.04)	0.11	0.64 (0.50, 0.82)	0.00035	0.63 (0.48, 0.83)	0.0013
rs2242656	BAT3	31722081	G	0.21	0.79 (0.68, 0.91)	0.0017	0.74 (0.59, 0.92)	0.0081	0.63 (0.48, 0.82)	0.00068	0.80 (0.60, 1.06)	0.12
rs7746553	C2	32003952	C	0.14	1.31 (1.11, 1.54)	0.0011	1.13 (0.89, 1.43)	0.31	1.68 (1.32, 2.14)	2.3E-05	1.59 (1.21, 2.10)	0.00090
rs8084	HLA-DRA	32519013	A	0.47	0.85 (0.76, 0.96)	0.0073	0.80 (0.67, 0.95)	0.012	0.67 (0.55, 0.82)	7.9E-05	0.92 (0.73, 1.14)	0.44
rs7192	HLA-DRA	32519624	A	0.43	0.84 (0.75, 0.95)	0.0040	0.80 (0.67, 0.95)	0.012	0.57 (0.46, 0.70)	1.1E-07	0.94 (0.75, 1.17)	0.57
rs1894408	HLA-DOB	32894811	G	0.36	1.23 (1.09, 1.39)	0.00076	1.17 (0.98, 1.39)	0.090	1.62 (1.33, 1.98)	1.5E-06	1.14 (0.91, 1.43)	0.27
rs241447‡	TAP2	32904728	G	0.24	1.34 (1.17, 1.53)	3.1E-05	1.08 (0.88, 1.32)	0.48	1.82 (1.46, 2.26)	6.9E-08	1.38 (1.08, 1.77)	0.011
rs714289	HLA-DMB	33013789	G	0.07	0.99 (0.78, 1.25)	0.93	1.02 (0.73, 1.43)	0.90	0.69 (0.44, 1.08)	0.11	1.00 (0.63, 1.56)	0.98

^*Ordinal OR and 95% confidence interval from the log additive model, adjusted for age and sex.

^†LOC100129921

^‡Top hit from Table 2.