Table 4.
Predicted novel disease genes using all confirmed genes
| Genes | Prob (%) | Relevant disease | References |
|---|---|---|---|
| GP5 | 99.2 | Bernard–Soulier syndrome | (Roth et al., 1990) |
| Gray platelet syndrome | (Berger et al., 1996) | ||
| Platelet disorder | (Shi et al., 2004) | ||
| Autoimmune thrombocytopenia | (Mayer et al., 1996) | ||
| Coagulopathy | (Modderman et al., 1992) | ||
| Thrombocytopenia | (Acar et al., 2008) | ||
| Thrombosis | (Ravanat et al., 1997) | ||
| ALG13 | 97.9 | ||
| ADPRHL1 | 96.7 | ||
| PARVA | 96.6 | Tumors | (Attwell et al., 2003) |
| Cancer | (Sepulveda et al., 2006) | ||
| ODAM | 96.4 | ||
| ANGPTL1 | 96.3 | Melanoma | (Smagur et al., 2005) |
| Tumors | (Xu et al., 2004) | ||
| PTK7 | 96.1 | Panic | (Eser et al., 2005) |
| Panic attacks | (van Megen et al., 1997) | ||
| Panic disorder | (Bradwejn et al., 1992) | ||
| Premenstrual dysphoric disorder | (Le Mellédo et al., 1999) | ||
| Effects cardiovascular | (Bradwejn et al., 1994) | ||
| Agoraphobia | (Koszycki et al., 1996) | ||
| Anxiety disorders | (Bradwejn et al., 1990) | ||
| Colon carcinoma | (Mossie et al., 1995) | ||
| WSB1 | 95.7 | neurobalstoma | (Chen, 2006) |
| AFF1 | 95.0 | Lymphoblastic leukemia acute | (Bertrand et al., 2001) |
| Acute leukemia | (Chen et al., 1993) | ||
| Leukemogenesis | (Yamamoto et al., 1998) | ||
| Leukemia | (Li et al., 1998) | ||
| Chromosomal aberrations | (Nakamura et al., 1993) | ||
| INHBB | 94.7 | Tumors | (Peschon et al., 1992) |
| MAPK12 | 94.4 | Shock | (Cuenda et al., 1997) |
| PHLDA1 | 94.3 | Tumors | (Nagai et al., 2007) |
| CABLES2 | 94.0 | ||
| BDH2 | 94.0 | ||
| CD97 | 94.0 | Thyroid carcinoma | (Hoang-Vu et al., 1999) |
| Thyroid carcinoma anaplastic | (Hoang-Vu et al., 1999) | ||
| Arthritis reactive | (Hamann et al., 1999) | ||
| Colorectal tumors | (Steinert et al., 2002) | ||
| Colorectal carcinoma | (Steinert et al., 2002) | ||
| SLC29A4 | 93.9 | ||
| FAIM | 93.8 | Leukemia, lymphocytic, Acute | (Ross et al., 2003) |
| EIF2AK2 | 93.8 | Virus infection | (Gil et al., 2000) |
| Vesicular stomatitis | (Lee et al., 1996) | ||
| Hepatitis c | (Hiasa et al., 2003) | ||
| Influenza | (Min et al., 2007) | ||
| Herpes simplex | (Smith et al., 2006) | ||
| KRT20 | 93.7 | Carcinoma merkel cell | (Cheuk et al., 2001) |
| Carcinoma mucinous | (Ji et al., 2002) | ||
| adenocarcinoma | (Chen et al., 2004) | ||
| ITGB1BP2 | 93.7 | Cardiac hypertrophy | (Brancaccio et al., 2003) |
| hypertrophy | (Palumbo et al., 2009) |