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Time to symptom improvement in laryngeal attack
| Open label | Double-blind (FAST-3) | ||||
|---|---|---|---|---|---|
|
|
|
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| FAST-1 (n = 8) | FAST-2 (n = 3) | FAST-3 (n = 5) | Icatibant (n = 3) | Placebo (n = 2) | |
| Time to first symptom improvement (according to patient) (hours) | 0.6 (NA) | 1 (NA) | 0.2 (NA) | 1 (0.6–2.5) | 2.1 (0.5–3.9) |
| Time to 50% reduction in symptom severity (hours) | NA | NA | 2.3 (1.5–4) | 2.5 (1.3–3) | 3.2 (1–5.4) |
Note: Values are expressed as median (interquartile range).
Abbreviation: NA, not available.
