Table 1.

After 12 weeks, quantitative computed tomographic analysis (QCT) was performed to measure bone mineral density (BMD), bone mineral content (BMC) and bony callus volume (BCV) [PDLLA poly-(D,L-lactide]

QCT (parameters)	Group 1 (n=8) cage + PDLLA	Group 2 (n=8) cage + PDLLA + IGF-I (0.5%) + TGF-β1 (2.5%)	Group 3 (n=8) cage + PDLLA + IGF-I (1%) + TGF-β1 (5%)	Group 4 (n=8) Cage + PDLLA + IGF-I (2%) + TGF-β1 (10%)
BMD (g/cm3)	0.62±0.03 (0.59–0.66)	0.62±0.03 (0.58–0.66)	0.64±0.04 (0.59–0.68)	0.65±0.04 (0.60–0.69)
BMC (g)	2.1±0.5 (1.3–2.6)	2.6±1.5 (2.7–5.8)	3.4±1.6a (2.4–5.5)	3.5±1.6a (2.4–5.5)
BCV (cm3)	3.4±0.9 (2.5–4.3)	4.2±1.1a (4.4–7.1)	5.2±1.2a,b (4.1–6.8)	5.4±1.0a,b (4.1–6.8)

^aP<0.05 in comparison to group 1

^bP<0.05 in comparison to group 2