Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Incidence of all-causality constipation in fixed-dose Phase III studies in OAB patients
| Constipation severity | Darifenacin 7.5 mg/day N = 337 |
Darifenacin 15 mg/d N = 334 |
Tolterodine 4 mg/d N = 223 |
Placebo N = 388 |
|---|---|---|---|---|
| Mild, N (%) | 29 (8.6) | 39 (11.7) | 15 (6.7) | 15 (3.9) |
| Moderate, N (%) | 19 (5.6) | 23 (6.9) | 9 (4.0) | 7 (1.8) |
| Severe, N (%) | 2 (0.6) | 9 (2.7) | 4 (1.8) | 2 (0.5) |
| Total | 50 (14.8) | 71 (21.3) | 28 (12.6) | 24 (6.2) |
Abbreviation: OAB, overactive bladder.
