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. 2012 Oct;16(10):1172–1178. doi: 10.1089/gtmb.2012.0120

Table 5.

Receiver Operating Characteristics Analysis for Prediction of Left Ventricular Ejection Fraction <40%

  AUC (95% CI)a Sig. Cutoff Sensitivity Specificity
TIMP-1 (nM) at admission 0.534(0.467; 0.601) 0.357 ≥78.70 94.4% 17.6%
TIMP-1 (nM) 24 h 0.616(0.538; 0.694) 0.005b ≥144.95 53.4% 70.4%
Troponin I (ng/mL) 0.700(0.630; 0.771) <0.001b ≥53.95 76.1% 58.1%
BNP (pg/mL) at admission 0.728(0.668; 0.788) <0.001b ≥79.80 76.4% 64.5%
BNP (pg/mL) 24 h 0.769(0.710; 0.827) <0.001b ≥299.70 80.3% 62.2%
a

AUC, area under the curve with 95% confidence interval (CI).

b

Significant p values.

TIMP, tissue inhibitors of metalloproteinase.