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. Author manuscript; available in PMC: 2013 Mar 1.
Published in final edited form as: Gynecol Oncol. 2011 Nov 22;124(3):589–597. doi: 10.1016/j.ygyno.2011.11.019

Figure 2. Effects of sunitinib in HOVTAX2.

Figure 2

A. Proliferation of both naïve and paclitaxel resistant cells show dose responsiveness to sunitinib at nM concentrations after 72 hrs. Data is plotted as cell number ± S.D. B. Western blot panel of cells treated with 50 nM sunitinib for 24 hrs showing that p-ERK is downregulated with no changes in p-AKT expression. β-actin is a loading control. C. Cell cycle analysis of cells starved for 24 hrs followed by 72 hr treatment of sunitinib in regular media. Data is plotted as cell phase percentage with stacking in G1 phase in response to sunitinib; more so, in naïve cells.