. Author manuscript; available in PMC: 2012 Oct 10.

Published in final edited form as: J Med Chem. 1994 Oct 14;37(21):3614–3621. doi: 10.1021/jm00047a018

Table 2.

Characterization of Intermediates and 2-Substituted-N ⁶-(3-iodobenzyl)adenosine Derivatives

compd	mp (°C)	formula	analysis
10	172	C₁₇H₁₈N₅O₄I	C, H, N
11	foam	C₁₇H₁₇N₅O₄ClI•0.3MeOH	C, H, N
12	152–154	C₁₇H₁₉N₆O₄I•1.2MeOH	C, H, N
13	206–207	C₁₈H₁₈N₆O₄ClI•0.5MeOH	C, H, N
14	190	C₁₉H₂₃N₇O₄I	^a
15	179	C₁₉H₂₁N₆O₄IS	^a
17	syrup	C₂₂H₃₀O₅Si	C, H
18	syrup	C₃₆H₃₈N₇Si	C, H
19	syrup	C₂₀H₂₀N₇	C, H, N
20	syrup	C₂₀H₁₈N₈•0.63H₂O	C, H
21	92.2–93.7	C₂₁H₂₀N₈	C, H
22	syrup	C₂₁H₂₁NO₇•0.5H₂O	C, H, N
23a,b	foam	C₂₂H₂₁NO₈•0.3H₂O	C, H, N
24a	222–224	C₁₂H₁₉N₅ClI	C, H, N
25	foam	C₃₂H₂₆N₆O₆ClI•1.0C₆H₁₄	C, H, N
26	foam	C₃₈H₂₉N₅O₇ClI0.2C₆H₁₄	C, H, N

High-resolution MS (m/z) measured in FAB⁺ mode. 14: calcd for C₁₉H₂₃N₇O₄I 540.0856, found 540.0867. 15: calcd for C₁₉H₂₁N₆O₄I₁S₁ 557.0468, found 557.0482.