Table 1. The average changes in van der Waals () and electrostatic () interaction energies (kcal/mol) between MTx and the surroundings due to the binding of MTx to Kv1.1–Kv1.3 channels.

Channel			(kT)
Kv1.1	−51±11	−416±55	−12.0
Kv1.2	−22±12	−17±76	−21.2
Kv1.3	−43±12	−265±67	−10.9

Standard deviations are shown. ΔG _bind is calculated as , where C₀ is 1 M. The IC₅₀ values are 6 µM, 0.6nM and 18 µM for Kv1.1, Kv1.2 and Kv1.3, respectively.