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. 2012 Jun 26;303(6):L528–L538. doi: 10.1152/ajplung.00167.2012

Fig. 5.

Fig. 5.

Evaluation of IL-13 content in BAL and mucus metaplasia in WT and Glrx1−/− mice subjected to sensitization and challenge with OVA. A: IL-13 content in the BAL was determined by ELISA. Data are expressed as means ± SE from 8 to 10 mice per group. *P < 0.05 (ANOVA) compared with respective alum/OVA control groups. †P < 0.05 (ANOVA) compared with WT OVA/OVA groups. B: mucus metaplasia was assessed in periodic acid Schiff-stained (PAS) bronchiolar epithelium from WT and Glrx1−/− mice sensitized and challenged with OVA (OVA/OVA). Mucus metaplasia was evaluated by obtaining 3 images of small bronchioles (×20 objective) of similar dimensions from each mouse. Average scores of 2 independent evaluations were determined. Data are expressed as means ± SE from 8 to 10 mice per group. *P < 0.05 (Kruskal-Wallis) compared with respective alum/OVA control groups. †P < 0.05 (Kruskal-Wallis) compared with WT OVA/OVA groups. Black bars: BALB/c mice, white bars: Glrx1−/− mice.