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Urine flow rate before (baseline) and during an intramedullary infusion of saline or the ETB receptor agonist sarafotoxin 6c (S6c) for 80 min in rats on a normal- or low-salt diet. Separate groups of rats were pretreated with the AT1 receptor antagonist candesartan for 2 wk before the study. ns, Not significant. *P < 0.05 vs. baseline period in the same group; n = 5–6 rats/group.
