Table 2.
Lipid profile and inflammatory biomarkers
Normal Activity | Activity Restricted | |
---|---|---|
Total cholesterol, mg/dl | 112 ± 8.0 | 129 ± 6.5 |
HDL cholesterol, mg/dl | 55 ± 5.3 | 61 ± 4.9 |
LDL cholesterol, mg/dl | 47 ± 8.7 | 56 ± 3.5 |
Triglycerides, mg/dl | 21 ± 5.2 | 41 ± 6.1* |
CRP, μg/ml | 0.15 ± 0.06 | 0.13 ± 0.04 |
Endothelin-1, pg/ml | 4.7 ± 2.9 | 15.4 ± 5.2 |
TNFα, pg/ml | NCR | NCR |
Interleukin-1, pg/ml | NCR | NCR |
Interleukin-8, pg/ml | 516 ± 72 | 1,269 ± 331 |
Interleukin-10, pg/ml | NCR | NCR |
MIP-1β, pg/ml | 135 ± 11 | 180 ± 24 |
PAI-1, ng/ml | 10.2 ± 1.2 | 19.7 ± 5.7 |
RANTES, ng/ml | 1.8 ± 0.3 | 8.3 ± 3.7 |
MDC, pg/ml | 46 ± 9.3 | 74 ± 8.8* |
Data are means ± SE. CRP, C-reactive protein; MIP, macrophage inflammatory protein-1β; MDC, monocyte-derived chemokine; NCR, non-cross reactive; PAI-1, plasminogen activator inhibitor-1; RANTES, regulated-on-activation normal T cell-expressed and -secreted chemokine;
P < 0.05 vs. normal activity. Data are parametric except for CRP, endothelin-1, MIP-1β, PAI-1, and RANTES.