Fig. 5.

Brain stem Pyy mRNA expression is reduced significantly in response to 24-h fasting, prolonged calorie restriction (CR), and following enterogastroanastomosis (EGA) procedure. A: change in brain stem Pyy mRNA expression in mice in response to 24-h fasting. B and C: changes in body weight and circulating leptin levels, respectively, in mice subjected to prolonged CR. D and E: changes in Pyy and Y1, Y2, and Y5 receptor mRNA expression levels in mice subjected to prolonged CR and in mice that underwent EGA procedure, respectively.