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. 2012 Jul 3;303(6):F873–F885. doi: 10.1152/ajprenal.00092.2012

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Fig. 5. — Kidney function as determined by serum creatinine and urine albumin/creatinine ratio after IRI, with and without EP and/or rHMGB1 treatment. Serum creatinine and albuminuria (urine albumin/creatinine ratio) were measured 36 h after IRI (40-min ischemia) and EP and/or rHMGB1 treatment. Serum creatinine and albuminuria were elevated in IRI animals; however, EP treatment blunted the rise in serum creatinine and albuminuria, an effect abolished by intravenous rHMGB1 injection. *P < 0.05 vs. control. +P < 0.05 vs. EP; n = 6.