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Inhibiting NO synthase in vitro increases pendrin label intensity. Top: micrographs of representative CCD (or CNTs) taken from the same mouse that were cultured in the presence of either NG-nitro-l-arginine methyl ester (l-NAME; 100 μM) or vehicle. Bottom: mean pendrin label intensity in CNTs and in CCDs cultured overnight in the presence of the NO synthase inhibitor l-NAME vs. vehicle. *P < 0.05.
