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. 2012 Oct 10;7(10):e47001. doi: 10.1371/journal.pone.0047001

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© 2012 Wang et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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: Phylogenetic analysis of the miR-1 family shows a similar evolution pattern in both platyhelminthes O. turkestanicum and Schistosoma japonicum. Panels c and d: Phylogenetic analysis of the miR-71 family shows distinct evolutionary differences between O. turkestanicum miRNA and those from other species. Full name and taxonomic classification: (a) cte: Capitella teleta; lgi: Lottia gigantea; otu: Orientobilhazia turkestanicum; sja: Schistosoma japonicum; spu: Strongylocentrotus purpuratus; sme: Schmidtea mediterranea; crm: Caenorhabditis remanei; cel: Caenorhabditis elegans; (b) up: nematodes and other invertebrates; down: variants of otu showed same mutation characteristics, but different with nematodes and other invertebrates above; (c) gga: Gallus gallus; crm: Caenorhabditis remanei; odi: Oikopleura dioica; oan: Ornithorhynchus anatinus; ssc: Sus scrofa; mmu: Mus musculus; mdo: Monodelphis domestica; sko: Saccoglossus kowalevskii; dme: Drosophila melanogaster; (d) up: nematodes; middle: Hemichordata, insect, bird, mammals; down: platyhelminthes. Star line (“*”): consensus sequence.