Relative mRNA levels of DHRS3 in liver of adult rats. A: kinetics of regulation of DHRS3 expression in liver of vitamin A-deficient rats after a single bolus dose of RA. Livers of vitamin A-deficient rats were analyzed 0, 3, 6, 10, and 16 h following injection of a single bolus dose of 100 μg RA, as previously reported (32). B: relative mRNA levels of DHRS3 mRNA in liver of rats fed vitamin A-deficient (VAD), -marginal (VAM), -adequate (VA-ad), and -supplemented (VASup) diets from weaning to 8 wk of age. Values are means ± SE; n = 5, 7, 6, and 2 rats for VAD, VAM, VA-ad, VASup, respectively. Different letters indicate significant difference: P < 0.05.