Table 1. Summary of the sequence variations in the M003-A06 genes in human populations and chimpanzee.
SNP | Locationa | Human | Chimpanzee | ||
H | C1 | C2 | |||
rs1667354 | 479 | A (Asp)b | G (splicing) | G (splicing) | A (Asp) |
rs935706 | 1039 | G (Ala) | A (Thr) | A (Thr) | G (Ala) |
rs935707 | 1130 | G (Arg) | A (His) | A (His) | A (His) |
rs1667363 | 1273 | A (Ser) | T (Cys) | T (Cys) | T (Cys) |
rs1667364 | 1280 | C (Ala) | A (Glu) | A (Glu) | A (Glu) |
rs16971886 | 1382 | G (Arg) | G (Arg) | A (His) | G (Arg) |
* | 1404 | T | T | T | C |
rs10405238 | 1462 | T (Tyr) | G (Asp) | T (Tyr) | T (Tyr) |
rs1345748 | 1604 | G (Cys) | A (Tyr) | A (Tyr) | A (Tyr) |
rs1363752 | 1706 | A (Glu) | G (Gly) | G (Gly) | G (Gly) |
rs1644698 | 1879 | C (Pro) | G (Ala) | G (Ala) | G (Ala) |
rs1363753 | 1888 | G (Gly) | C (Arg) | C (Arg) | C (Arg) |
rs1667366 | 1906 | T (Stop) | C (Arg) | C (Arg) | C (Arg) |
rs3745770 | 1972 | C (-) | C (Arg) | G (Gly) | C (Arg) |
The sequence variations among the H, C1, C2 alleles of human M003-A06 and the chimpanzee M003-A06 gene are listed. The amino acid changes at the non-synonymous SNPs are indicated in the parentheses. The single synonymous nucleotide difference between the human and chimpanzee is indicated by the star.
The synonymous nucleotide difference between human and chimpanzee.
The locations of SNPs relative to A (+1) of the start codon (ATG).
The amino acids at the non-synonymous sites.