Table 2. Odds ratios and 95% confidence intervals for TP53 Arg72Pro genotypes or alleles and breast cancer risk.
unadjusted | adjusted* | |||||
Genotypes/Alleles | OR | 95% CI | p-value | OR | 95% CI | p-value |
Pro/Pro vs. Arg/Arg | 2.38 | 1.01–5.93 | 0.046 | 3.06 | 0.74–12.67 | 0.111 |
Pro/Pro vs. Arg/Pro | 1.68 | 0.71–4.23 | 0.247 | 2.02 | 0.47–8.66 | 0.325 |
Arg/Pro vs. Arg/Arg | 1.41 | 0.98–2.05 | 0.067 | 1.53 | 0.91–2.58 | 0.113 |
Pro/Pro + Arg/Pro vs.Arg/Arg | 1.49 | 1.04–2.14 | 0.028 | 1.63 | 0.98–2.71 | 0.060 |
Pro/Pro vs. Arg/Pro +Arg/Arg | 2.03 | 0.87–4.73 | 0.089 | 2.55 | 0.63–10.37 | 0.164 |
Pro vs. Arg | 1.46 | 1.08–1.99 | 0.013 | 1.60 | 1.02–2.50 | 0.036 |
Analyses of breast cancer cases vs. controls of the indicated genotypes or Pro vs. Arg alleles are shown. 95% CI, 95% confidence intervals. *adjusted for age and menopausal status.