Figure 9. Graph showing relative fold change expression of RANK, RANKL and OPG for WT and TLR4^−/− mice (mean fold change over day 0; ND, not detectable).

Expression levels of RANK, RANKL and OPG were realtively constant in WT at all time points. Greater variation of the three genes was detected in TLR4^−/− (mean +/−SEM; n = 5 to 7).