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. 2012 Oct 10;7(10):e46321. doi: 10.1371/journal.pone.0046321

Figure 6. Effects of intra-amygdala administration of ghrelin on anxiety-like behavior in rats given access to food.

Figure 6

In rats given access to food during the first hour after intra-amygdala injection (FOOD ACCESS), ghrelin increased food intake relative to saline controls (g of chow), both during this hour and during the 1 hr measurement taken after the anxiety tests (A). In this paradigm there was no effect of ghrelin (relative to saline controls) on anxiety-like behavior in either the EPM test (time spent in the open arm; B) or the open field test (central activity or central rearing; C, D respectively). *P<0.05 **P<0.01, vs. saline. Independent samples t-test, SPSS.