Table 4. Comparison of the genotype frequencies of missense mutations and indel polymorphisms in the open reading frame of SPRN gene between cattle and buffalo.
Frequency | ||||
Position# | Amino acidchange | Genotype | Cattle | Buffalo |
188 | Ala63Val | C/C | 0.995 | 1.000 |
C/T | 0.005 | 0.000 | ||
199 | indel AAAG | wt/wt | 0.941 | 1.000 |
12-bp ins/12-bp ins | 0.005 | 0.000 | ||
12-bp del/wt | 0.010 | 0.000 | ||
12-bp ins/wt | 0.045 | 0.000 | ||
236 | Ser79Trp | C/C | 1.000 | 0.988 |
C/G | 0.000 | 0.012 | ||
259 | Pro87Thr | C/C | 0.995 | 1.000 |
C/A | 0.005 | 0.000 | ||
262 | Ala88Pro | G/G | 0.995 | 1.000 |
G/C | 0.005 | 0.000 | ||
269 | Leu90Pro | T/T | 1.000 | 0.988 |
T/C | 0.000 | 0.012 | ||
274 275 | *Pro92Thr/Met | C/C C/C | 1.000 | 0.000 |
A/A C/C | 0.000 | 0.725 | ||
A/A C/T | 0.000 | 0.263 | ||
A/A T/T | 1.000 | 0.012 | ||
304 | Ser102Gly | A/A | 1.000 | 0.000 |
G/G | 0.000 | 1.000 | ||
355 | Thr119Ala | A/A | 1.000 | 0.000 |
A/G | 0.000 | 1.000 | ||
G/G | 0.000 | 1.000 | ||
365 | *Thr122Ile | C/C | 0.985 | 0.162 |
C/T | 0.015 | 0.413 | ||
T/T | 0.000 | 0.425 | ||
367 | Gly123Ser | G/G | 1.000 | 0.922 |
G/A | 0.000 | 0.066 | ||
A/A | 0.000 | 0.012 | ||
415 | *Arg139Trp | C/C | 1.000 | 0.689 |
C/T | 0.000 | 0.257 | ||
T/T | 0.000 | 0.054 | ||
425 | Arg142Gln | G/G | 0.965 | 1.000 |
G/A | 0.035 | 0.000 |
Nucleotide number corresponds to the coding region of SPRN sequence.
Denotes significant differences in genotype frequencies between cattle and buffalo.
Letters in boldface and italics indicate fixed differences between cattle and buffalo.