Table 6. Comparison of putative transcription factor bind sites in SPRN gene between cattle and buffalo.

Transcription factor	Binding site position*	Mutation†	Strand	Binding site	Binding site in cattle	Binding site in buffalo
AML-1a	−368	g.987T>C	+	TGCGGT	have	no
GATA-3	−293	g.1066C>A	+	GGGATTGGG	no	yes
CP2	−287	g.1075A>G	−	TGGGGTCGGGC	no	yes
P300	−214	g.1143	+	GCGGGGGGTGCGA	yes	no
JCV_repeat_sequence	−157	g.1202T>G	+	GGGTGGGG	no	yes
PuF	−157	g.1202T>G	+	GGGTGGG	no	yes
AP-2	−157	g.1202T>G	−	GGGTGGGG	no	yes
AML-1a	−153	g.1202T>G	+	TGGGG	yes	no
CP2	−153	g.1202T>G	-	T GGGGGTGCGC	yes	no
Ik-2	+309	g.1638G>A	+	GGGTGGGACT	no	yes
Ik-2	+309	g.1672A>G	+	GCCTGGGAAAG	yes	no
USF	+438	g.1799–1800CA>TG	+	CCACATG	no	yes
USF	+441	g.1799–1800CA>TG	−	CCACATG	no	yes
MZF1	+456	g.1814G>C	−	CCCCAGG	no	yes
GATA-1, GATA-2	+496	g.1856T>A	−	CCCATCCTC	no	yes
Sp1	+496	g.1878T>C	−	CCACGCCCC	no	yes
Sp1	+645	g.2004G>A	−	GCCCGCCCC	yes	no
RREB-1	+638	g.2004G>A	+	CCCCAGCCCACCC	no	yes
AML-1a	+646	g.2004G>A	−	ACCCCA	no	yes

^*The binding site position is given with respect to the transcription factor start site (position 1355 in GenBank accession number DQ058606).

^†Mutation indicates the nucleotide change from the cattle to the buffalo sequence. For example, g.987T>C indicates that in position 987 there is a T and C in the sequences of cattle and buffalo, respectively.