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. 2012 Oct 10;7(10):e46969. doi: 10.1371/journal.pone.0046969

Table 1. Effects of 1.4 mM sodium salicylate (NaSal) on action potential properties (n = 10).

Measurements Before NaSal perfusion After NaSal perfusion
Threshold (mV)1 −31.3 ± 1.4 −29.3 ± 1.6*
Amplitude (mV)2 68.0 ± 2.7 63.4 ± 2.8**
Rise slope (mV/ms) 83.4 ± 11.9 72.4 ± 11.9*
Decay slope (mV/ms) −32.6 ± 3.1 −29.0 ± 2.7**
Half-width (ms) 1.5 ± 0.1 1.6 ± 0.1*
Threshold current (pA)3 44.5 ± 6.7 77.5 ± 11.8***

All data are expressed as means ± SEM. *, ** and *** indicate P<0.05, P<0.01 and P<0.001, respectively (paired Student's t-test).

1

The action potential threshold was defined as the membrane potential at which the potential of the membrane began to rise rapidly and the neuron generated only one or two spikes.

2

The action potential amplitude was calculated by subtracting the threshold from the peak value of the action potential.

3

The threshold current was defined as the minimum current that is required to elicit one or two spikes.