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. Author manuscript; available in PMC: 2013 Dec 15.
Published in final edited form as: Pediatr Blood Cancer. 2012 Sep 4;59(7):1160–1167. doi: 10.1002/pbc.24272

Fig. 1. Major causes and consequences of obesity in childhood cancer patients and/or survivors with recommended interventions.

Fig. 1

Obesity is attributed to multiple etiologies depending on patient tumor type and treatment. Due to metabolic and neuroendocrine alterations, increased energy intake, and decreased energy expenditure, fat mass increases. Obesity is associated with increased morbidity and mortality in patients and survivors. Behavioral, pharmacologic, and/or surgical interventions are necessary to prevent, reduce, and diminish excessive weight gain during and following treatment.