Table 2.

Body and organ weights of rats in acute toxicity study in control and groups treated with different doses of L. elliptica essential oil

Parameter	Control	Treatment of Litsea elliptica essential oil
		500 mg/kg	1 000 mg/kg	2 000 mg/kg	2 500 mg/kg	3 000 mg/kg
Body weight loss (%)
Day 7	5.98±0.08	5.03±0.07	4.80±0.02	3.63±0.05	2.44±0.04	0.98±0.02
Day 14	10.29±0.13	7.91±0.09	7.43±0.05	5.32±0.06a	3.90±0.04a	2.46±0.04c
Absolute weight (g)
Liver	7.81±1.04	7.84±1.29	8.67±0.90	8.41±1.29	8.35±0.77	8.52±0.78
Renal	1.34±0.06	1.34±0.07	1.03±0.05b	1.01±0.08b	1.28±0.10d	1.51±0.11b d e
Spleen	0.44±0.10	0.48±0.06	0.45±0.08	0.48±0.16	0.50±0.11	0.49±0.18
Heart	0.32±0.03	0.33±0.03	0.35±0.03	0.36±0.03	0.39±0.05b	0.39±0.07b
Relative weight (%)
Liver	3.40±0.48	3.49±0.58	3.87±0.38	3.86±0.56	3.92±0.40	4.09±0.26
Renal	0.58±0.04	0.60±0.04	0.46±0.02b	0.46±0.03b	0.60±0.05d	0.73±0.06b d e
Spleen	0.19±0.04	0.27±0.03	0.20±0.03	0.22±0.07	0.23±0.05	0.24±0.10
Heart	0.14±0.01	0.15±0.02	0.15±0.01	0.16±0.02	0.18±0.02a	0.19±0.03a

Data are expressed as mean±SEM, n=10 for each group

^aSignificant at P<0.05 as compared with control only

^bSignificant at P<0.05 as compared with the control and 500 mg/kg

^cSignificant at P<0.05 as compared with the control, 500 and 1 000 mg/kg

^dSignificant at P<0.05 as compared with 1 000 and 2 000 mg/kg

^eSignificant at P<0.05 as compared with 2 500 mg/kg