Table 3.
Body and organ weights of rats in subacute toxicity study in control and groups treated with different doses of L. elliptica essential oil
| Parameter | Control | Treatment of Litsea elliptica essential oil |
||
| 125 mg/kg | 250 mg/kg | 500 mg/kg | ||
| Body weight (g) | ||||
| Day 0 | 200.00±2.89 | 197.00±2.13 | 198.00±1.87 | 197.00±2.00 |
| Day 7 | 209.00±4.33 | 208.00±2.50 | 207.00±2.90 | 201.50±3.42 |
| Day 14 | 212.50±4.30 | 212.00±2.71 | 211.50±3.66 | 204.50±2.93 |
| Day 21 | 214.50±4.68 | 213.00±3.67 | 213.00±3.51 | 210.50±4.68 |
| Day 28 | 217.50±4.90 | 217.00±3.35 | 214.00±4.58 | 212.50±3.75 |
| Absolute weight (g) | ||||
| Liver | 5.53±0.86 | 5.98±0.93 | 5.69±0.80 | 6.09±0.38 |
| Renal | 1.29±0.15 | 1.37±0.13 | 1.34±0.21 | 1.35±0.12 |
| Spleen | 0.38±0.07 | 0.44±0.07 | 0.45±0.07 | 0.45±0.10 |
| Heart | 0.75±0.09 | 0.72±0.07 | 0.75±0.08 | 0.71±0.11 |
| Pancreas | 1.16±0.32 | 1.01±0.23 | 1.02±0.17 | 1.02±0.34 |
| Relative weight (%) | ||||
| Liver | 2.54±0.34 | 2.76±0.38 | 2.65±0.29 | 2.87±0.18 |
| Renal | 0.60±0.06 | 0.63±0.06 | 0.63±0.07 | 0.64±0.04 |
| Spleen | 0.18±0.03 | 0.21±0.04 | 0.21±0.03 | 0.21±0.03 |
| Heart | 0.35±0.05 | 0.34±0.02 | 0.35±0.04 | 0.33±0.04 |
| Pancreas | 0.54±0.13 | 0.47±0.10 | 0.48±0.07 | 0.48±0.15 |
Data are expressed as mean±SEM, n=10 for each group. No statistical difference was found between the control and L. elliptica essential oil treated groups (P>0.05)