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Clinical scoring of disease in mice after aerosol exposure to LVS grown in different culture media. Mice were scored daily beginning the day of exposure and continuing through day 10 after infection for changes in behavior and appearance. Mice were exposed to aerosols containing LVS grown in (A) MHb, (B) CCDM, and (C) BHI at a range of doses (n = 10 per dose). Graphs show average daily score for each group; error bars show standard deviation.
