Table 3.
# | Author | Year | Compound | Strain | Dose | Rote | Test | (Model) |
---|---|---|---|---|---|---|---|---|
1 | Nagase et al. | 2002 | TAN-67 | SD | 1-10 mg/kg | s.c. | FSS | |
2 | Broom et al. | 2002 | SNC80 | SD | 10-100 mg/kg | s.c. | FSS | |
3 | Broom et al. | 2002 | (+) BW373U86 | SD | 1-10 mg/kg | s.c. | FSS | |
4 | Saitoh et al. | 2004 | SNC80 | ICR | 0.3-3 mg/kg | s.c. | FSS/CSM | |
5 | Torregrossa et al. | 2005 | (+) BW373U86 | SD | 10 mg/kg X 1, 8, 21 days | s.c. | FSS | |
6 | Naidu et al. | 2007 | (-) NIH11082 | C57BL6 | 8-32 mg/kg | i.p. | TST | |
7 | Saitoh et al. | 2008 | SNC80 | Wistar | 1-10 mg/kg X 7 days | s.c. | HE | OB rat model |
8 | Vergra et al. | 2008 | UFP-512 | Swiss | 0.001-0.1 nmol/0.01-1 mg/kg | i.c.v./i.p. | FSS | |
9 | UFP-512 | SD | 0.1-1 mg/kg | i.p. | FSS | |||
10 | Le Bourdonnec et al. | 2008 | ADL5859 | - | 0.3-3 mg/kg | p.o. | FSS | |
11 | Saitoh et al. | 2011 | KNT-127 | ICR | 0.1-1 mg/kg | s.c. | FSS | |
12 | Hudzik et al. | 2011 | AZD2327 | SD | 1-10 mg/kg X 4 days | p.o. | LH |
Abbreviation; FSS: Forced swim test, CSM: Conditioned suppressive motility, HE: Hyperemotionality score, LH: Learned helplessness test