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. 2012 Aug 30;4(9):870–881. doi: 10.1093/gbe/evs073

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© The Author(s) 2012. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 1.— — DNA flexibility as defined by the four phosphate linkages in the codon (TRX). (A) External linkages are defined by neighboring adjacent codons, whereas internal linkages are defined by the codon itself. Adjacent codons are displayed with alternating stick and wireframe display. (B) A strong and highly significant correlation (r = 0.66, P < 0.0001, df = 193) exists between the sum flexibility(TRX score) and the average minor groove width (angstroms) of tetramers in free DNA and protein-bound DNA structures reported in Rohs et al. (2009).