Table 2.
Th cell-related cytokine changes of RA patients compared with healthy control.
| Cytokine | RA (n = 76) | Control (n = 18) | Z | P |
|---|---|---|---|---|
| TGF-β | 159.9 ± 13.2 | 156.0 ± 6.4 | 1.8 | 0.078 |
| IL-17A | 48.7 ± 20.2∗ | 32.5 ± 7.1 | 4.2 | <0.001 |
| IFN-γ | 5.4 ± 3.2∗ | 3.6 ± 0.7 | 3.4 | 0.001 |
| TNF-α | 4.9 ± 4.3∗ | 3.5 ± 0.8 | 3.7 | <0.001 |
| IL-10 | 7.1 ± 3.4∗ | 5.1 ± 2.3 | 4.0 | <0.001 |
| IL-6 | 15.8 ± 42.1∗ | 6.8 ± 3.2 | 4.3 | <0.001 |
| IL-4 | 14.6 ± 5.0∗ | 10.9 ± 2.0 | 4.3 | <0.001 |
| IL-2 | 14.4 ± 4.6∗ | 11.1 ± 1.4 | 4.7 | <0.001 |
Values are expressed as median ± interquartile range; the differences between RA and control groups were assessed by Wilcoxon test; ∗P values less than 0.001 were considered significant.