TABLE 3.
Multiplier to the incidence of effect/benefit | |
EPA severity ranking of effects | |
NOEL (no effect) | 0 |
NOAEL (nonadverse effect) | 1 |
(LO)AEL (adverse effect) | 2 |
FEL (frank toxicity) | 3 |
“Severity” ranking of benefits | |
None | 0 |
Minimal (decreased arthritis) | 1 |
Moderate (lower blood pressure) | 2 |
Maximum (decreased CHD) | 3 |
Note. CHD, coronary heart disease; FEL, frank effect level; LOAEL, lowest observed adverse effect level; NOAEL, no observed adverse effect level; NOEL, no observed effect level.
Please note the intended association of the term “severity” with “benefits.” In order to balance risks with benefits, matching schemes, and terminology, seem appropriate.