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. 2012 Oct 5;5:147–158. doi: 10.2147/CCID.S30794

Table 1.

Five categories of facial filler approved by Health Canada

Category Agent Durationa
High-viscosity, low molecular weight hyaluronic acid (LMWHA) Voluma (Allergan, Inc) Long duration (up to 18 months)5,6
Hyaluronic acid (HA) Juvéderm (Allergan, Inc) Intermediate duration (~12 mo)6
Restylane (Medicis Aesthetics) Intermediate duration (~6 mo)4
Perlane (Medicis Aesthetics)
Teosyal (Clarion Medical Technologies)
Esthelis (Anteis)
Prevelle (Mentor)
Revanesse (Prollenium Medical)
Calcium hydroxylapatite Radiesse (Merz Aesthetics) Intermediate duration (~1 yr)7
Poly-L-lactic acid (PLLA) Sculptra (Valeant) Long duration (up to 18 months)8
Polymethyl methacrylate (PMMA) Artefill (Artes Medical/suneva) Permanent (~10 years)4
Platelet-Rich Fibrin Matrix (PRFM) Selphyl (Canderm) Long duration (up to 18 months)

Note:

a

Some authors have seen duration of action which is longer than the amounts selphyl (Canderm) listed above.