Table 3.
Genotype distribution of TLR9-1486T/C promoter polymorphism.
| SNP | Genotypes | Total | Allele frequency | |||
|---|---|---|---|---|---|---|
| TT | TC | CC | C | T | ||
| Non-CAD | 46 | 41 | 12 | 99 | 65 (32.8%) | 133 (67.2%) |
| CAD | 135 | 147 | 51 | 333 | 249 (37.4%) | 417 (62.6%) |
| P | χ 2 = 1.304 P = 0.521 | χ 2 = 1.371 P = 0.242 | ||||
|
| ||||||
| Non-DM | 91 | 103 | 34 | 239 | 171 (37.5%) | 285 (62.5%) |
| DM | 79 | 85 | 29 | 193 | 143 (37%) | 243 (63%) |
| P | χ 2 = 0.058 P = 0.971 | χ 2 = 0.018 P = 0.892 | ||||
|
| ||||||
| Control | 23 | 37 | 6 | 66 | 49 (37.1%) | 83 (62.9%) |
| CAD | 69 | 76 | 28 | 173 | 132 (38.2%) | 214 (61.8%) |
| DM | 13 | 14 | 6 | 33 | 26 (39.4%) | 40 (60.6%) |
| DM + CAD | 66 | 71 | 23 | 160 | 117 (36.6%) | 203 (63.4) |
| P | χ 2 = 4.258 P = 0.642 | χ 2 = 0.292 P = 0.962 | ||||
Control: control group; CHD: CAD group; DM: T2DM group; DM + CAD = type 2 diabetes mellitus plus coronary artery disease group.