Table 1.

Comparison of CEPH HLA Bw4/Bw6 and HLA C1/C2 allelic control population to the UT/OR and AGRE allele frequencies.

	CEPH Controls	UT/OR(n=70)				AGRE(n=88)				Combined UT/OR & AGRE(n=158)
		UT/OR	OR	95% CI	p- value	AGRE	OR	95% CI	p- value	Both	OR	95% CI	p- value
no Bw4	29	11	1			21	1			32	1
Bw4	123	56	1.2	(0.56, 2.58)	0.639	60	0.67	(0.35, 1.28)	0.227	116	0.85	(0.49, 1.50)	0.585
B15	9	3	0.88	(0.2, 3.89)	0.864	7	1.07	(0.34, 3.36)	0.902	10	1.01	(0.36, 2.84)	0.999
no Bw4	29	11	1			21	1			32	1
Bw4 80I	107	33	0.69	(0.39, 1.21)	0.192	36	0.55	(0.32, 0.93)	0.026	69	0.60	(0.39, 0.93)	0.021
Bw4 80T	102	30	0.64	(0.36, 1.14)	0.124	29	0.45	(0.26, 0.78)	0.004	59	0.52	(0.33, 0.81)	0.004
B15 or B27	31	12	0.87	(0.40, 1.87)	0.715	23	1.43	(0.75, 2.71)	0.270	35	1.17	(0.67, 2.06)	0.573
no C1	30	12	1			13	1			25	1
C1	134	58	1.08	(0.52, 2.27)	0.834	75	1.29	(0.63, 2.63)	0.480	133	1.19	(0.66, 2.14)	0.556
no C2	64	19	1			38	1			57	1
C2	100	51	1.72	(0.93, 3.18)	0.084	50	0.84	(0.5, 1.43)	0.522	101	1.13	(0.72, 1.78)	0.585
Bw6/Bw6	29	11	1			21	1			32	1
Bw4/Bw6	92	40	1.15	(0.52, 2.53)	0.734	44	0.66	(0.34, 1.29)	0.223	84	0.83	(0.46, 1.49)	0.524
Bw4/Bw4	31	16	1.36	(0.54, 3.43)	0.512	16	0.71	(0.31, 1.63)	0.421	32	0.94	(0.46, 1.90)	0.853
Bw6/B15	9	3	0.88	(0.20, 3.89)	0.864	7	1.07	(0.34, 3.36)	0.902	10	1.01	(0.36, 2.84)	0.999
C1/C1	64	19	1			38	1			57	1
C2/C1	70	39	1.88	(0.98, 3.59)	0.056	37	0.89	(0.50, 1.57)	0.687	76	1.22	(0.75, 1.98)	0.421
C2/C2	30	12	1.35	(0.58, 3.14)	0.488	13	0.73	(0.34, 1.57)	0.419	25	0.94	(0.49, 1.78)	0.839

Bold type p-values significant at the p≤0.05 level.