Table 3.
Comparison of inhibitory (i) and activating (a) KIR genes between the CEPH control population and the UT/OR and AGRE autistic populations separately and together.
| CEPH Controls |
UT/OR(n=70) | AGRE(n=88) | Combined UT/OR & AGRE(n=158) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UT/OR | OR | 95% CI | p- value |
AGRE | OR | 95% CI | p- value |
Both | OR | 95% CI | p- value |
||
| iKIR | 176 | 67 | 0.71 | (0.43, 1.19) | 0.194 | 88 | 0.72 | (0.44, 1.17) | 0.188 | 155 | 0.71 | (0.47, 1.07) | 0.097 |
| aKIR | 128 | 54 | 1.41 | (1.13, 1.76) | 0.002 | 72 | 1.32 | (1.08, 1.61) | 0.007 | 126 | 1.36 | (1.15, 1.61) |
0.0004 0.034* |
| iKIR + HLA | 147 | 67 | 0.81 | (0.57, 1.15) | 0.244 | 88 | 0.69 | (0.50, 0.97) | 0.033 | 155 | 0.76 | (0.58, 1.01) | 0.062 |
| aKIR + HLA | 104 | 49 | 1.74 | (1.25, 2.40) | 0.001 | 68 | 1.48 | (1.09, 2.01) | 0.012 | 117 | 1.56 | (1.21, 2.02) |
0.0006 0.050* |
Bold type p-values are significant at the p≤0.05 level. Bonferroni allelic corrected p-values significant at the p≤0.05 are listed below in Bold type*.