Table 1.
Pt. no. | Age at onset of SJS/TEN (years) | Inciting agent for SJS/TEN | Self-reported drug allergies | Time after surgery when acetazolamide started (months) | Presence of glaucoma drainage tube pre-acetazolamide | Time on acetazolamide (months) | Adverse reactions to acetazolamide |
---|---|---|---|---|---|---|---|
1 |
43 |
ibuprofen |
NSAID |
1 day |
Y |
10 days |
Warmth and pruritis |
2* |
48 |
sulindac |
NSAID |
24 |
N |
1 |
N |
3 |
40 |
allopurinol, erythromycin, colchicine |
same |
9 |
Y |
9 |
N |
4 |
50 |
Not known |
terfenadine |
0 |
N |
31 |
N |
5 |
3 |
PCN |
PCN, sulfa, erythromycin |
5 |
N |
1.5 |
N |
6 |
36 |
Not known |
PCN, cefazolin, erythromycin |
2 |
Y |
24 |
N |
7 |
54 |
bupropion, atenolol |
same |
13 |
Y |
30 |
N |
8 |
25 |
Not known |
NKDA |
7 |
Y |
24 |
N |
9 |
13 |
aspirin, ibuprofen |
same |
0.75 |
Y |
1.5 |
N |
10 |
Not known |
Not known |
PCN, codeine |
Not known |
Not known |
9 |
N |
11 | 27 | PCN | PCN, sulfa | 2 | Y | 64 | N |
*This patient received a Boston keratoprosthesis type I.
PCN: penicillin; NSAID: nonsteroidal anti-inflammatory drug.