Table 1. Ultrastructural damage is strongly reduced in persephone homozygotes versus wild-type siblings after neomycin exposure.

Treatment	Genotype	A–B	C	D	E
mock	pers/pers	4	0	0	2
	pers/+	3	0	0	2
	+/+	4	2	0	4
50 µM Neo	pers/pers	7	1	0	2
	pers/+	3	2	0	2
	+/+	2	0	0	2
200 µM Neo	pers/pers	5	2	1	2
	pers/+	0	0	3	2
	+/+	1	0	5	4

n = number of fish in each category.

Damage scale:

A = All hair cells of the neuromast appear normal.

B = Slight mitochondrial swelling (modest within range of mock-treated controls).

C = One or more hair cells exhibit some mitochondrial swelling. One or more hair cells also exhibit some nuclear condensation.

D = Many hair cells show severe damage, including distended mitochondria, highly pycnotic nuclei, or condensation of the entire cell.

E = Hair cells are absent, or all hair cells show severe damage, including severely distended mitochondria, highly pycnotic nuclei, or condensation of the entire cell.