Figure 5. Histological examinations. LM, light microscopic examinations; EM, electron microscopic examinations; DLK1, RTL1 and DIO3, immunohistochemical examinations for the corresponding proteins. The arrows and arrowheads in the EM findings indicate endothelial cells and pericytes, respectively. Scale bars represent 100 μm for 1–4, 15–18, 23–26 and 31–34, 50 μm for 5–8, 19–22 and 27–30, 5 μm for 9–11 and 2 μm for 12–14. Gestational age, placental weight, and % placental weight assessed by the gestational age-matched Japanese references for placental weight^4,22are described.