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. 2012 Oct 11;7(10):e47123. doi: 10.1371/journal.pone.0047123

Figure 5. Survival of Y. pestis Lux reporters in macrophages.

Figure 5

RAW264.7 macrophages were infected with Y. pestis Lux reporter strains, extracellular bacteria killed by gentamicin, and bacterial survival monitored by CFU determination (A–C) or bioluminescence (D–F). Data from WT Y. pestis is represented by black symbols and from an attenuated ΔphoP mutant by white symbols. (A and D) are strains with the LuxPEM7 reporter (n = 3 for CFU, n = 24 for RLU), (B and E) are strains with the LuxPtolC reporter (n = 3 for CFU, n = 12 for RLU), and (C and F) are strains with the LuxPcysZK reporter (n = 3 for CFU, n = 12 for RLU).