. 2012 Oct 11;7(10):e47305. doi: 10.1371/journal.pone.0047305

Table 2. Metastats Analysis of Differential Abundance.

Phylum	Class	Order	Family	Genus
Actinobacteria	Actinobacteria	↑Coribacteriales^AD	↑Coriobacteriaceae^A	↑Atopobium^A
				↑Cryptobacterium^ABC
				↑Olsenella^A
		↓Rubrobacterales^C	↓Rubrobacterineaceae^C	↓Rubrobacter^C
		Actinomycetales	Nocardioidaceae	↑Nocardioides^ABC
			↑Micrococcaceae^AC	↓Arthrobacter^A
				↑Rothia^AC
			Propionibacteriaceae	↓Propionibacterium^B
			↑Kineosporiaceae^D
			↑Cellulomonadaceae^C	↑Tropheryma^C
			↑Actinomycetaceae^A	↑Actinomyces^A
			↓Geodermatophilaceae^AC	↓Modestobacter^AC
			↓Nakamurellaceae^ABC	↓Humicoccus^ABC
		Bifidobacteriales	Bifidobacteriaceae	↑Bifidobacterium^A
Firmicutes	Bacilli	Bacillales	Bacillalaceae	↑Pontibacillus ^BC
			↓Thermoactinomycetaceae^ABC	↓Thermoactinomyces^ABC
		↑Lactobacillales^AD	↑Streptococcaceae^AD	↑Streptococcus^A
			↑Aerococcaceae^ABC	↑Abiotrophia^ABC
	Erysipelotrichi	↑Erysipelotrichales^A	↑Erysipelotrichaceae^A	↑Bulleidia/↑Solobacterium^A
	Negativicutes	Selenomonadales	↑Veillonellaceae^A	↑Dialister^A
				↑Veillonella^A
				↑Selenomonas^A
				↑Centipeda^A
	Clostridia	Clostridiales	↑Lachnospiraceae^A	↑Catonella^A
				↑Oribacterium^A
				↑Butyrivibrio^A
			↑Eubacteriaceae^A	↑Eubacterium^A
			Clostridiaceae	↑Anaerosporobacter^A
				↑Clostridium ^BC
				↓Anaerobacter^A
			Peptostreptococcaceae	↓Sporacetigenium^BC
				↑Peptostreptococcus^A
			Unclassified Clostridales	↑Howardella^D
			Clostridales incerta sedis	↑Parvimonas^A
↑Fusobacteria^A	↑Fusobacteria^A	↑Fusobacteriales^A	↑Leptotrichiaceae^A	↑Leptotrichia^A
			↑Fusobacteriaceae^A	↑Fusobacterium^A
Proteobacteria	α-proteobacteria	↑Rhodospirillales^A	↑Bradyrhizobiaceae^BC	↑Balneimonas ^ABC
		Sphingomonadales	↑Sphingomonadaceae^B
	β-proteobacteria	↑Neisserales^A	Neisseriaceae	↑Kingella^ABC
	γ-proteobacteria	↑Aeromonadales ^ABC	↑Aeromonadaceae ^ABC	↑Aeromonas ^AB
		Pseudomonadales	Pseudomonadaceae	↑Azomonas^BC
		Enterobacteriales	Enterobacteriaceae	↑Serratia^A
				↓Citrobacter^ABC
				↑Enterobacter^BC
		↑Cardiobacteriales^D
	δ-proteobacteria	↑Desulfobacterales ^ABC	↑Desulfobulbaceae ^ABC	↑Desulfobulbus^AC
		↑Desulfovibrionales^D
	↑ε-proteobacteria^A	↑Campylobacteriales^A	↑Campylobacteriaceae^A	↑Campylobacter^A
Acidobacteria	↑Group 3 ^ABC
Bacteroidetes	Bacteroidia	Bacteroidales	Porphyromonadaceae	↑Dysgonomonas^ABC
				↑Tannerella^A
			Prevotellaceae	↑Prevotella^A
				↑Hallella^A
			Unclassified Bacteroidales	↑Phocaeicola^BCD
			↑Bacteroidales incerta sedis^BCD
	Flavobacteria	Flavobacteriales	Flavobacteriaceae	↑Planobacterium^BC
				↑Capnocytophaga^AC
Synergistetes	↑Synergistia^D	↑Synergistales^D
↑SR1^BC				↑SR1 genera incertae sedis ^BC
↑TM7^A				↑TM7 genera incerta sedis^A

Change in abundance in COPD (compared to Control).

Change in abundance in 14 subjects using inhaled corticosteroids (compared to all other COPD samples and controls).

Change in abundance in 16 subjects using inhaled bronchodilators (compared to all other COPD samples and controls).

Change in abundance in 7 COPD samples in the left lower quadrant (compared to all other COPD samples and controls).

Bolded Taxa were differentially expressed in Severe COPD (compared to Moderate COPD).