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Resident F4/80-immunoreactive macrophages (amorphous cells, red) were present principally in lamina propria of the mucosa in control colorectums. TNBS induced an infiltration of monocytes (round, red cells) in the submucosa (SM) and an increase in macrophages in the lamina propria on day 2, which was diminished on day 14 and resolved by days 28–42. Tissue sections were counterstained with DAPI (nuclei in blue).
