Fig. 5.

Effect of TNBS on responses of serosal and mucosal afferents. A: TNBS transiently (at day 14 posttreatment) reduced responses of serosal afferents to graded probing (0.4, 1, and 1.4 g); responses did not differ from saline on days 28 and 56. TNBS treatment was accompanied by reduced proportions of fibers activated by 0.4 g probing at days 14 and 28 after treatment, which recovered by day 56 (C). Responses of mucosal afferents to either graded probing (B) or mucosal stroking (D) were not affected by TNBS treatment. AP, action potential; *P < 0.05; **P < 0.01.