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. 2012 Aug 17;303(8):H919–H930. doi: 10.1152/ajpheart.00577.2012

Fig. 1.

Fig. 1.

Key future areas of research for the cardiovascular matrix metalloproteinase (MMP) field. MMP function and regulation remain to be investigated from multiple perspectives, including needs for better understanding of time and expression pattern, substrate specificity patterns, and the role of MMPs, tissue inhibitors of MMPs (TIMPs), or substrates as markers of disease progression or treatment efficacy. MMP imaging techniques provide a promising avenue for future research.