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. 2012 Aug 3;303(8):H989–H1000. doi: 10.1152/ajpheart.00416.2012

Fig. 1.

Fig. 1.

Effect of duration of incubation of isolated cardiomyocytes in 25 mM glucose on phosphorylation of MYPT1 (A) and LIM kinase (LIMK) 1/2 (B) as indexes of Rho kinase (ROCK) activity. *p<0.05 compared with the first group (n = 4–6). C: effect of the ROCK inhibitor Y-27632 (1 μM) treatment on ROCK activity in cardiomyocytes incubated in 25 mM glucose for 24 h. Mannitol was used as an osmotic control. *P < 0.05 compared with the other groups (n = 4–6). D: effect of the ROCK inhibitors Y-27632 (1 μM) and H-1152 (1 μM) treatment for 24 h on RhoA expression in cardiomyocytes incubated in 25 mM glucose. *P < 0.05 compared with the other groups (n = 7).