Table 3.
Denervation, Tissue, and Group | Norepinephrine, ng/g |
---|---|
Experiment 2—lumbar denervation | |
Left soleus | |
Sham | 66 ± 13 |
LDNx | 9 ± 2* |
Right soleus | |
Sham | 65 ± 12 |
LDNx | 21 ± 8* |
Experiment 3—renal denervation | |
Left kidney | |
Sham | 134 ± 12 |
RDNx | 4 ± 1* |
Right kidney | |
Sham | 122 ± 14 |
RDNx | 6 ± 1* |
Experiment 4—celiac ganglionectomy | |
Liver | |
Sham | 33 ± 6 |
CGx | 6 ± 1* |
Spleen | |
Sham | 189 ± 34 |
CGx | 2 ± 0.1* |
Duodenum | |
Sham | 455 ± 42 |
CGx | 6 ± 2* |
Experiment 5—adrenal demedullation | |
Left adrenal | |
Sham | 156,146 ± 44,059 |
ADMx | 868 ± 611* |
Right adrenal | |
Sham | 116,090 ± 24051 |
ADMx | 359 ± 136* |
Values are means ± SE. Norepinephrine content (in ng/g tissue) was an indicator of successful denervation. Tissue was analyzed from the soleus muscles in the hindlimb to assess lumbar denervation; the kidneys to assess renal denervation; the spleen, liver, and duodenum to assess celiac ganglionectomy; and the adrenal glands to assess adrenal demedullation.
P < 0.05 vs. sham group.