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. 2012 Oct 11;7(10):e46769. doi: 10.1371/journal.pone.0046769

Figure 6. The effect of FGFR-2IIIc siRNA on mRNA expression in the GCT stromal cells.

Figure 6

(a). FGFR2 siRNA transfection resulted in a 70% decrease in FGFR-2IIIc expression in GCT stromal cells. (b). Quantitative RT-PCR was used to represent the expression of ALP, Runx2 and TWIST following FGFR-2IIIc knockdown (KO) in GCT cells. Results are the average of three replicate experiments. FGFR-2IIIc knockdown resulted a 1.5 fold increase of TWIST1 expression and a significant decrease in Runx2 and ALP expression (p<0.05).